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The digestive tract does degrade some of the molecule, but not all of it

The study revealed no significant difference in the overcorrection incidence between the proactive (16.7%) and reactive (28%) groups (p = 0.54)

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Another study found that participants regained an average of 11.6% of their body weight within a year after stopping treatment

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In patients with primary or secondary hyperoxaluria, nephrolithiasis, acute or chronic oxalate nephropathy, or chronic kidney disease irrespective of aetiology, one or more of these elements are disrupted